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CLINICAL TRIALS

TRIALS
Click on Program Name for More Information about Prevention Program

The Lynne Cohen High Risk Clinic at Bellevue Hospital Center, NYU Cancer Institute

1. NYU 00-60: Cancer Screening and Prevention Program for High Risk Women
2. GOG – 199: Study of Risk- Reducing Salpingo-Oophorectomy and CA-125 screening among women with an increased genetic risk of ovarian cancer.
3. Pilot Study of Letrozole in High Risk Postmenopausal Women for Prevention of Breast Cancer Breast Cancer (trial has completed accrual,analysis in process)
4. Is it possible to increase the specificity of the breast MRI by a fusion technique with PET scanning?
5. Attitudes toward Genetic Risk among underserved women at Familial risk for Cancer
6. Breast cancer chemoprevention by SOM230, and IGF-1 inhibitor


The Lynne Cohen High Risk Screening and Prevention Project for Ovarian and Breast Cancer at M.D. Anderson Cancer Center

1. GYN01-142: Risk of Ovarian Cancer Algorhythm. Study of assessing if CA-125 is helpful in early detection of ovarian cancer among women who have a BRCA mutation and are over 30 years of age. 
2. Lab03-0479: Prospective follow-up of women at increased risk for breast cancer.
3. ID02-458: Pilot biomarker breast cancer prevention study using Celebrex.

The Lynne Cohen Preventive Care Clinic for Women's Cancers at USC/Norris Comprehensive Cancer Center

1. 1B-04-3 Screening Breast Ultrasound in High-Risk Women. Looking at the role of screening breast ultrasound vs. mammography for the early detection of cancer.
2. GOG-190: Fenretinide used as a chemoprevention agent for women undergoing prophylactic Oophorectomy.
3. GOG-199: Study of Risk-Reducing Salpingo-Oophorectomy and CA-125 screening among women with an increased genetic risk of ovarian cancer.
4. 50-04-1 Serum Proteomics: To study the role of proteomic pattern analysis as an early detection tool for high risk women who are undergoing prophylactic surgery.

The Lynne Cohen Breast Cancer Preventive Care Program at NYU Cancer Institute

1. NYU 00-60: Cancer Screening and Prevention Program for High Risk Women
2. GOG – 199: Study of Risk- Reducing Salpingo-Oophorectomy and CA-125 screening among women with an increased genetic risk of ovarian cancer.
3. Pilot Study of Letrozole in High Risk Postmenopausal Women for Prevention of Breast Cancer
4. Is it possible to increase the specificity of the breast MRI by a fusion technique with PET scanning?

The Lynne Cohen Preventive Care Program for Women's Cancers at University of Alabama, Birmingham

1. UAB 0413: A Phase III Randomized Study of Exemestane vs. Placebo in Postmenopausal Women at Increased Risk of Developing Breast Cancer
2. UAB 485: Serum Proteomics for the Detection of Ovarian Cancer: A Multi-Site Study Using the Correlogic Systems, Inc. Serome Pattern Blood Test System (Serum Proteomics for the Detection of Ovarian Cancer: A Multi-Site Study Using the Correlogic Systems, Inc. Proteome Pattern Blood Test System)
3. Ovarian Spore Project: Array-based analysis of primary and metastatic ovarian tumors to identify risk factors/predisposing genetic elements for ovarian cancer, as well as genetic heterogeneity associated with ovarian cancer spread and progression.

The NCI Clinical Trials


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